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Massive giant-cell tumor of pelviacetabulum : ウィキペディア英語版 | Massive giant-cell tumor of pelviacetabulum
Giant-cell tumor (GCT) of the pelvis is uncommon, accounting for only 1.5 to 6% of cases of GCT.〔Cheng MT, Chen TH, Chen WM. Periacetabular giant cell tumor treated with intralesional excision and allograft reconstruction. J Chin Med Assoc 2004;67:537-41〕 In pelvis ilium is the most common site of involvement; ischium and pubis are less frequently involved.〔Patne SC, Kumar M, Sadaf L. Giant-cell tumor of the pubic bone: A case report. Int J Orthop Surg 2009;15:1148〕 It typically presents in adults between age of 20 to 50 with localized swelling and pain.〔Blake SM, Gie GA. Large pelvic giant cell tumor: A case report and a review of current treatment modalities. J Arthroplasty 2004;19:1050-4〕 Females are slightly more affected than males.〔Sanjay BK, Frassica FJ, Frassica DA. Treatment of giant-cell tumor of the pelvis. J Bone Joint Surg Am 1993;75:1466-75〕 Average size of the tumor in this region is 9.5 cm.〔Sanjay BK, Frassica FJ, Frassica DA. Treatment of giant-cell tumor of the pelvis. J Bone Joint Surg Am 1993;75:1466-75〕 There are different modalities of treatment of pelvic GCT. Radiotherapy has high rate of recurrence (44%) and risk of soft tissue sarcomas (12%).〔Leggon RE, Zlotecki R, Reith J. Giant Cell Tumor of the pelvis and sacrum. Clin Orthop Relat Res 2004;423:196-207〕 Thus treatment should be essentially surgical which includes surgical excision. Excision can be extralesional which achieves 90% local tumor control but poor functional outcome 〔Gitelis S, Mallin BA, Piasecki P. Intralesional excision compared with en bloc resection of giant cell tumors of bone. J Bone Joint Surg 1993;17:1648-55〕 or it can be intralesional which has 90% local recurrence rate with good functional outcome.〔Bloodgood JC. The conservative treatment of giant cell sarcoma, with the study of bone transplantation. Ann Surg 1912;56:210-39〕
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